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Lineage commitment of dermal fibroblast progenitors is controlled by Kdm6b-mediated chromatin demethylation
Mouse
Back Skin
Wounded Whole Cells
scRNAseq, scATACseq
E14.5, E16.5, P5
Male
Quan Phan
Ryan Driskell
Parallel Single-Cell Multiomics Analysis of Neonatal Skin Reveals the Transitional Fibroblast States that Restrict Differentiation into Distinct Fates
Mouse
Back Skin
Wounded Whole Cells
scRNAseq, scATACseq
P0
Male
Sean Thompson
Ryan Driskell
Parallel Single-Cell Multiomics Analysis of Neonatal Skin Reveals the Transitional Fibroblast States that Restrict Differentiation into Distinct Fates
Mouse
Back Skin
Wounded Fibroblast Subset
scRNAseq, scATACseq
P0
Male
Sean Thompson
Ryan Driskell
Lef1 expression in fibroblasts maintains developmental potential in adult skin to regenerate wounds
Mouse
Back Skin
Whole Cells
scRNAseq
P2-P21
Male
Quan Phan
Ryan Driskell
Lef1 expression in fibroblasts maintains developmental potential in adult skin to regenerate wounds
Mouse
Back Skin
Fibroblast Subset
scRNAseq
P2-P21
Male
Quan Phan
Ryan Driskell
Single-cell transcriptomic analysis of small and large wounds reveals the distinct spatial organization of regenerative fibroblasts
Mouse
Back Skin
Wounded Whole Cells
scRNAseq
P2-P21
Male
Quan Phan
Ryan Driskell
Single-cell transcriptomic analysis of small and large wounds reveals the distinct spatial organization of regenerative fibroblasts
Mouse
Back Skin
Wounded Fibroblast Subset
scRNAseq
P2-P21
Male
Quan Phan
Ryan Driskell